In Red Dead Redemption 2, Arthur will be infected with Tuberculosis (TB) during the Chapter 5. This affects the gameplay and many players wonder if there's any way to heal Arthur but unfortunately there is no cure to his disease.
After the infection with TB in the mission "Paradise Mercifully Departed" Arthur must live with some health restrictions. The disease will fully developed after completion of Chapter 5. You can see he falls off his horse and is diagnosed by a doctor in a cutscene Chapter 6.
The disease will affect all cores and will empty faster. Under normal conditions, it takes 90 minutes for cores to be completely consumed. With the disease, the time is reduced to only 75 minutes.
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The core loss is actually no big deal, because they can be completely regenerated in no time. This can be done with some rest, bathing or eating. You don’t even have to go to a hotel or return to the main camp.
You can always set up your own small camp in the wilds. You can select this via the menu or activate it with the quick function, if you hold down triangle / Y briefly. After a short rest you are fit again and can continue to play, so that tuberculosis hardly restricts you.
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